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Syn-Flex Ends Arthritis in Humans and Pets

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The pain of osteoarthritis almost always begins gradually, progressing slowly over many years. People under 40 may have the condition with no symptoms at all. Osteoarthritis is commonly identified by the following symptoms:

  • Aching pain in one or more joints, stiffness, and loss of mobility.
  • Inflammation may or may not be present.
  • Stiffness tends to follow periods of inactivity, such as sleep or sitting, and can be eased by stretching and exercise.
  • The pain may behave like a roller coaster, with bad spells followed by periods of relative relief.
  • Pain seems to increase in humid weather.
  • It often worsens after extensive use of the joint and is more likely to occur at night than in the morning. As the disease advances, the pain may occur even when the joint is at rest and can keep a sufferer awake at night.
  • Osteoarthritis in the knee may cause a crackling like noise (called crepitus) when moved.


It would be impossible to discuss in this report all the numerous conditions that have symptoms of joint aches and pains. Something as benign as sleeping on a bad mattress to the serious afflictions associated with cancer can mirror symptoms of osteoarthritis. Other problems that can cause aches and pains in the joints include physical injuries, infections, and poor circulation. A number of rare genetic diseases attack the joints.

Osteoarthritis can generally be distinguished from other joint diseases by considering a number of factors together: osteoarthritis usually occurs in older people and is located in only one or a few joints; the joints are less inflamed than in other arthritic conditions, and progression of pain is almost always gradual.

A few of the most common disorders that can be confused with, or may even accompany, osteoarthritis are worth noting.

Rheumatoid Arthritis

Osteoarthritis may be confused with rheumatoid arthritis, particularly when osteoarthritis affects multiple joints in the body. Rheumatoid arthritis begins in the synovial membrane rather than the cartilage. It normally occurs earlier in life than osteoarthritis, often striking people in their 30s and 40s. Many joints are affected, and rheumatoid arthritis often occurs symmetrically on both sides of the body. People generally have morning stiffness that lasts for at least an hour. (Stiffness from osteoarthritis usually clears up within half an hour.) X-rays show changes in the bones that differ from those occurring in osteoarthritis. In rheumatoid arthritis, blood tests often show a specific antibody, known as rheumatoid factor, that is not present with osteoarthritis. In another blood test, levels of a factor called erythrocyte sedimentation rate (ESR) are often elevated in rheumatoid arthritis, but they are generally normal in osteoarthritis. Rheumatoid arthritis also does not usually show up in the fingertips where osteoarthritis is common.


Chondrocalcinosis is a disease in which certain calcium crystals known as CPPD (calcium pyrophosphate dihydrate) are deposited in the joints. It may affect 25% of the population and can accompany and even exacerbate osteoarthritis. The problem has been called pseudogout or pseudo-osteoarthritis, in the latter case particularly when it affects the knees. A physician can usually differentiate between the two disorders, however, because chondrocalcinosis usually damages other joints (such as wrists, elbows, and shoulders) that are not normally affected by osteoarthritis.

Charcot's Joints

Charcot's joint occurs when an underlying disease, usually diabetes, causes nerve damage in the joint, which leads to swelling, bleeding, increased temperature, and changes in bone. There may be a loss of sensation that leads to an increased risk for injury from overuse.

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